BackgroundLow Emission Zones (LEZs) are areas where the most polluting vehicles are restricted from entering.The effectiveness of LEZs to lower ambient exposures is under debate.This study focused on LEZs that restricted cars of Euro 1 standard without appropriate retrofitting systems from entering and estimated LEZ effects on NO2, NO, and NOx (
Abstract Background Methylation of serotonin-related genes has been proposed as a plausible gene-by-environment link which may mediate environmental stress, depressive and anxiety symptoms.DNA methylation is often measured in blood cells, but little is known about the association between this peripheral epigenetic modification and brain serotonergi
Abstract Background There is under-diagnosis of cardiovascular disease (CVD) in the English population, despite financial incentives to encourage general practices to register new cases.We compared the modelled (expected) and diagnosed (observed) prevalence of three cardiovascular conditions- coronary heart disease (CHD), hypertension and stroke- a